Article Per Year (5 Year)
p-Index From 2019 - 2024
0.23
P-Index
This Author published in this journals
All Journal Jurnal Anestesi Perioperatif Majalah Kedokteran Nusantara The Journal Of Medical School Jurnal Neuroanestesi Indonesia Sumatera Medical Journal
Hasanul Arifin
Unknown Affiliation
Education Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Neuroscience Public Health Social Sciences

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Majalah Kedokteran Nusantara The Journal Of Medical School

 1 
Pengaruh pemberian klonidine 75 μg oral pre operatif terhadap tramadol hydrochloride 2.5mg/kgbb/iv untuk penatalaksanaan nyeri paska bedah Andri Faizal L; Hasanul Arifin; Syamsul Bahri
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 2 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction : Post surgical pain is an important problem in the process of operation, so that a strong analgesia is needed in the post-surgery. Already popular opioid used as an analgesic tramadol hydrochloride one, but use a single dose require large doses resulting in severe side effects. Preemptive method is one method to produce a satisfactory analgesia. In this study aimed to compare the combination of tramadol hydrochloride 2.5mg / kg / IV and oral clonidine 75•g for pain management after orthopedic surgery extremities.Methods : After the approval of the ethics committee of FK-USU, 45 samples were collected, men and women, from the age of 18- 40 years with ASA physical status 1-2, 1-4 preoperative VAS, who underwent elective orthopedic extremity surgery with general anesthesia Adam Malik Hospital. Samples were then randomly divided into 2 groups with 23 subjects each. This study used a randomized controlled clinical trial double-blind. Group A received tramadol hydrochloride 2.5mg / kg / IV IV and 75 mg oral clonidine. Group B received tramadol hydrochloride 2.5mg / kg / IV and placebo. Systolic and diastolic blood pressure, pulse frequency VAS values were recorded and measured. All data were analyzed using chi-square test and the crosstab. Results : VAS value in hours and hours to 6 to 8 significant difference clinically and statistically significant in both groups, with P = 0:02 on the clock to 6 and P = 0.00 at 8 hours.Conclusion : The result showed that a combination of tramadol hydrochloride with oral clonidine produces better analgesic than tramadol hydrochloride.Keywords : tramadol hydrochloride; klonidine; visual analogue score (VAS)
Co-Authors Andri Faizal L Andri, Mufti Dadik Wahyu Wijaya Fadinie, Wulan Fithri, Dewi Yuliana Franz Josef Tarigan Hafniana, Hafniana Hanafie, Achsanuddin Heru Kurniawan Heru Kurniawan Irina, Sinta Mufti Andri Mursin, Chairul M. Putra, Angga Permana Rehatta, Nancy Margareta Saleh, Siti Chasnak Syamsul Bahri Umar, Nazaruddin Wijaya, Dadik Wahyu Wijaya, Dadik Wahyu